Research Publications


Schuelein R, Spencer H, Dagley LF, Li PF, Luo L, Stow JL, Abraham G, Naderer T, Gomez-Valero L, Buchrieser C, Sugimoto C, Yamagishi J, Webb AI, Pasricha S, Hartland EL. Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL. Cell Microbiol. 2018 Apr 24. doi: 10.1111/cmi.12852.

Deo P, Chow SH, Hay ID, Kleifeld O, Costin A, Elgass KD, Jiang JH, Ramm G, Gabriel K, Dougan G, Lithgow T, Heinz E, Naderer TOuter membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis. PLoS Pathog. 2018 Mar 30;14(3):e1006945. doi: 10.1371/journal.ppat.1006945. eCollection 2018 Mar.

Saunders EC, Naderer T, Chambers J, Landfear SM, McConville MJ. Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models.  Mol Microbiol. 2018 Feb 7. doi: 10.1111/mmi.13923.

Naderer T, Fulcher MC. Targeting apoptosis pathways in infections. J Leukoc Biol. 2018 Feb;103(2):275-285. doi: 10.1189/JLB.4MR0717-286R.

Naderer T. Towards re-purposing BH3-mimetics in Legionella and viral infections. Expert Rev Anti Infect Ther. 2017 Dec;15(12):1071-1073. doi: 10.1080/14787210.2017.1409621.


Speir M, Vogrin A, Seidi A, Abraham G, Hunot S, Han Q, Dom GW II, Masters SL, Flavell RA, Vince JE, Naderer T. Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin. Front Cell Infect Microbiol., 7:35. DOI: 10.3389/fcimb.2017.00035

An Y, Wang J, Li C, Revote J, Zhang Y, Naderer T, Hayashida M, Akutsu T, Webb GI, Lithgow T, Song J. SecretEPDB: a comprehensive web-based resource for secreted effector proteins of the bacterial types III, IV and VI secretion systems. Sci Rep., 7:41031. DOI:  10.1038/srep41031


Speir M, Lawlor KE, Glaser SP, Abraham G, Chow S, Vogrin A, Schulze KE, Schuelein R, O’Reilly LA, Mason K, Hartland EL, Lithgow T, Strasser A, Lessene G, Huang DC, Vince JE, Naderer T. Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis, Nat Microbiol., 1:15034. DOI: 10.1038/nmicrobiol.2015.34

Tucey TM, Verma-Gaur J, Nguyen J, Hewitt VL, Lo TL, Shingu-Vazquez M, Robertson AA, Hill JR, Pettolino FA, Beddoe T, Cooper MA, Naderer T, Traven A. The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals. mSphere, 1:3. DOI: 10.1128/mSphere.00074-16

Chow SH, Deo P, Naderer T. Macrophage cell death in microbial infections. Cell Microbiol, 18:4. DOI: 10.1111/cmi.12573

Rolando M, Escoll P, Nora T, Botti J, Boitez V, Bedia C, Daniels C, Abraham G, Stogios PJ, Skarina T, Christophe C, Dervins-Ravault D, Cazalet C, Hilbi H, Rupasinghe TW, Tull D, McConville MJ, Ong SY, Hartland EL, Codogno P, Levade T, Naderer T, Savchenko A, Buchrieser C. Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc Natl Acad Sci U S A., 113:7. DOI: 10.1073/pnas.1522067113


Deen NS, Gong L, Naderer T, Devenish RJ, Kwok T. Analysis of the Relative Contribution of Phagocytosis, LC3‐Associated Phagocytosis, and Canonical Autophagy During Helicobacter pylori Infection of Macrophages. Helicobacter, 20:6. DOI: 10.1111/hel.12223

Naderer T, Heng J, Saunders EC, Kloehn J, Rupasinghe TW, Brown TJ, McConville MJ. Intracellular survival of Leishmania major depends on uptake and degradation of extracellular matrix glycosaminoglycans by macrophages. PLoS Pathog., 11(9):e1005136. DOI: 10.1371/journal.ppat.1005136

Tucey T, Naderer T, Traven A. Candida and macrophages: a deadly affair. Microbiology Australia, 36(2), 53-56. DOI: 10.1071/MA15019 


Sansom FM, Ralton JE, Sernee MF, Cohen AM, Hooker DJ, Hartland EL, Naderer T, McConville MJ. Golgi-located NTPDase1 of Leishmania major is required for lipophosphoglycan elongation and normal lesion development whereas secreted NTPDase2 is dispensable for virulence. PLoS Negl Trop Dis., 8(12): e3402. DOI:  10.1371/journal.pntd.0003402

Traven A, Naderer T. Microbial egress: a hitchhiker’s guide to freedom. PLoS Pathog., 10 (7), e1004201. DOI:  10.1371/journal.ppat.1004201

Uwamahoro N, Verma-Gaur J, Shen HH, Qu Y, Lewis R, Lu J, Bambery K, Masters SL, Vince JE, Naderer T, Traven A. The pathogen Candida albicans hijacks pyroptosis for escape from macrophages. mBio, 5(2), e00003-14. DOI:  10.1128/mBio.00003-14

Speir M, Vince JE, Naderer T. Programmed cell death in Legionella infection. Future Microbiol., 9(1), 107-118. DOI: 10.2217/fmb.13.139


Heng J, Saunders EC, Gooley PR, McConville MJ, Naderer T, Tull D. Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major. Mol Biochem Parasitol., 190(1):1-5. DOI: 10.1016/j.molbiopara.2013.05.005

Sansom FM, Tang L, Ralton JE, Saunders EC, Naderer T, McConville MJ. Leishmania major methionine sulfoxide reductase A is required for resistance to oxidative stress and efficient replication in macrophages. PLoS One, 8(2), e56064. DOI: 10.1371/journal.pone.0056064


Dolezal P, Aili M, Tong J, Jiang JH, Marobbio CM, Lee SF, Schuelein R, Belluzzo S, Binova E, Mousnier A, Frankel G, Giannuzzi G, Palmieri F, Gabriel K, Naderer T, Hartland EL, Lithgow T. Legionella pneumophila secretes a mitochondrial carrier protein during infection. PLoS Pathog., 8(1):e1002459. DOI: 10.1371/journal.ppat.1002459

Celik N, Webb CT, Leyton DL, Holt KE, Heinz E, Gorrell R, Kwok T, Naderer T, Strugnell RA, Speed TP, Teasdale RD, Likic VA, Lithgow T. A bioinformatic strategy for the detection, classification and analysis of bacterial autotransporters. PLoS One, 7(8): e43245. DOI: 10.1371/journal.pone.0043245

Tull D, Heng J, Gooley PR, Naderer T, McConville MJ. Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major. Int J Parasitol., 42(3): 239-247. DOI: 10.1016/j.ijpara.2011.12.004


Link to publications prior to 2012.